olopatadine Nasal

oh-loe-PA-ta-deen

Commonly used brand name(s)

In the U.S.

• Patanase

Available Dosage Forms:

• Spray

Therapeutic Class: Nasal Agent

Pharmacologic Class: Antihistamine

Uses For olopatadine

Olopatadine nasal spray is used to treat the symptoms of seasonal (short-term) allergic rhinitis (hay fever), such as sneezing, itchy or runny nose, or itchy eyes. It is an antihistamine and works by preventing the release of histamine in the body. Olopatadine will also block the effects of histamine, which prevents the allergic symptoms.

olopatadine is available only with your doctor's prescription.

Before Using olopatadine

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For olopatadine, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to olopatadine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Appropriate studies have not been performed on the relationship of age to the effects of olopatadine in children younger than 6 years of age. Safety and efficacy have not been established.

Geriatric

Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of olopatadine in the elderly. However, elderly patients are more likely to have age-related liver, kidney, or heart problems, which may require caution and an adjustment in the dose for patients receiving olopatadine.

Pregnancy

	Pregnancy Category	Explanation
All Trimesters	C	Animal studies have shown an adverse effect and there are no adequate studies in pregnant women OR no animal studies have been conducted and there are no adequate studies in pregnant women.

Breast Feeding

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Interactions with Medicines

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Tell your healthcare professional if you are taking any other prescription or nonprescription (over-the-counter [OTC]) medicine.

Interactions with Food/Tobacco/Alcohol

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

Other Medical Problems

The presence of other medical problems may affect the use of olopatadine. Make sure you tell your doctor if you have any other medical problems, especially:

• Injury to the inside of the nose or


• Nasal ulceration (sores or ulcers in the nose) or


• Nosebleeds—Use with caution. May make these conditions worse.

Proper Use of olopatadine

Use olopatadine only as directed by your doctor. Do not use more of it, do not use it more often, and do not use it for a longer time than your doctor ordered.

olopatadine comes with patient instructions. Read and follow these instructions carefully. Ask your doctor if you have any questions.

olopatadine is for use only in the nose. Do not get it in your eyes or on your skin. If it does get on these areas, rinse it off right away with water.

To use:

• When you use the spray for the first time, you must prime the bottle. To do this, pump the bottle 5 times or until the spray comes out. Now it is ready to use.


• If you do not use the bottle for 7 days or longer, prime it again by releasing 2 sprays.


• Before using the spray, gently blow your nose to clear the nostrils.


• After using the spray, wipe the tip of the bottle with a clean tissue and put the cap back on.

Dosing

The dose of olopatadine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of olopatadine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

• For nasal dosage form (spray):
  
  • For symptoms of hay fever:
    
    • Adults, teenagers, and children 12 years of age and older—2 sprays in each nostril two times per day.
    
    
    • Children 6 to 11 years of age—1 spray in each nostril two times per day.
    
    
    • Children younger than 6 years of age—Use and dose must be determined by your doctor.
    
    
  
  

Missed Dose

If you miss a dose of olopatadine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Precautions While Using olopatadine

It is very important that your doctor check you or your child at regular visits for any problems or unwanted effects that may be caused by olopatadine.

olopatadine may increase your risk of having nasal problems. Check with your doctor right away if you or your child have bloody mucus; sores inside the nose; or unexplained nosebleeds while you are using olopatadine.

olopatadine will add to the effects of alcohol and other CNS depressants (medicines that make you drowsy or less alert). Some examples of CNS depressants are antihistamines or medicine for hay fever, allergies, or colds; sedatives, tranquilizers, or sleeping medicine; prescription pain medicine or narcotics; medicine for seizures or barbiturates; muscle relaxants; or anesthetics, including some dental anesthetics. Check with your medical doctor or dentist before taking any of the medicines above while you or your child are using olopatadine.

olopatadine may cause some people to become dizzy, drowsy, or less alert than they are normally. If any of these side effects occur, do not drive, use machines, or do anything else that could be dangerous if you are dizzy or not alert.

If your or your child's symptoms do not improve within a few days or if they become worse, check with your doctor.

olopatadine Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

Less common

• Bladder pain


• bloody nose


• bloody or cloudy urine


• difficult, burning, or painful urination


• frequent urge to urinate


• lower back or side pain


• sore throat

Rare

• Chills


• cough


• diarrhea


• fever


• general feeling of discomfort or illness


• headache


• joint pain


• loss of appetite


• muscle aches and pains


• nausea


• runny nose


• shivering


• sweating


• trouble sleeping


• unusual tiredness or weakness


• vomiting

Incidence not known

• Difficulty with breathing or swallowing


• dizziness


• fast heartbeat


• shortness of breath


• skin itching, rash, or redness


• swelling of the face, throat, or tongue


• unpleasant breath odor


• vomiting of blood

Get emergency help immediately if any of the following symptoms of overdose occur:

Symptoms of overdose

• Anxiety


• deep or fast breathing with dizziness


• dry mouth


• irregular heartbeats


• irritability


• nervousness


• numbness of the feet, hands, and around the mouth


• restlessness


• shaking


• sleepiness

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

• Bitter taste

Rare

• Throat irritation

Incidence not known

• Thirst

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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More olopatadine Nasal resources

• Olopatadine Nasal Use in Pregnancy & Breastfeeding
• Olopatadine Nasal Drug Interactions
• Olopatadine Nasal Support Group
• 7 Reviews for Olopatadine Nasal - Add your own review/rating

• Patanase Prescribing Information (FDA)


• Patanase Spray MedFacts Consumer Leaflet (Wolters Kluwer)


• Patanase Consumer Overview

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